TIZANIDINE+ACECLOFENAC
About
TIZANIDINE+ACECLOFENAC is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
TIZANIDINE+ACECLOFENAC contains Tizanidine (muscle relaxant) and Aceclofenac (NSAID). Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac works by blocking the effect of prostaglandins which cause pain and inflammation. Thereby, reduces mild to moderate pain and inflammation. Together, TIZANIDINE+ACECLOFENAC helps in relieving pain due to muscle spasms.
You are advised to take TIZANIDINE+ACECLOFENAC for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Consult your doctor if you are pregnant or breastfeeding. TIZANIDINE+ACECLOFENAC may cause drowsiness and dizziness, so drive with caution. TIZANIDINE+ACECLOFENAC is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with TIZANIDINE+ACECLOFENAC as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions.
Uses of TIZANIDINE+ACECLOFENAC
Medicinal Benefits
TIZANIDINE+ACECLOFENAC is a combination of two drugs, namely: Tizanidine and Aceclofenac. TIZANIDINE+ACECLOFENAC is a combination medicine used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, and headache. Tizanidine is a muscle relaxant that works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac is an analgesic that works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make another chemical prostaglandins which are produced at injury sites and cause pain and swelling. By blocking the effect of COX enzymes, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, TIZANIDINE+ACECLOFENAC helps in relieving pain due to muscle spasms.
Directions for Use
Storage
Side Effects of TIZANIDINE+ACECLOFENAC
- Nausea
- Vomiting
- Stomach pain
- Diarrhoea
- Loss of appetite
- Heartburn
In-Depth Precautions and Warning
Drug Warnings
Do not take TIZANIDINE+ACECLOFENAC if you are allergic to any of its components. Inform your doctor if you have/ had high blood pressure, heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of the intestine, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. TIZANIDINE+ACECLOFENAC may cause drowsiness and dizziness, so drive only if you are alert. TIZANIDINE+ACECLOFENAC is not recommended for children as safety and effectiveness have not been established. Stop taking TIZANIDINE+ACECLOFENAC and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools.
Drug Interactions
Drug-Drug Interactions: TIZANIDINE+ACECLOFENAC may interact with pain killers (hydrocodone), anti-depressants (citalopram, escitalopram, duloxetine, fluoxetine, fluvoxamine, paroxetine, sertraline, lithium), hypnotic (zolpidem), anti-convulsant (pregabalin), antihistamine (diphenhydramine)
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have/had stomach ulcer or perforation, bleeding problems, bypass surgery, heart attack, blood circulation problems, heart problems, inflammation of intestines, anaemia, severe kidney or liver problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking TIZANIDINE+ACECLOFENAC as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.
Pregnancy
cautionPlease consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor if you are breastfeeding; your doctor will decide whether TIZANIDINE+ACECLOFENAC can be taken by breastfeeding mothers or not.
Driving
cautionTIZANIDINE+ACECLOFENAC may cause dizziness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.
Children
unsafeTIZANIDINE+ACECLOFENAC is not recommended for children as safety and effectiveness are not established.
Habit Forming
Diet & Lifestyle Advise
- Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
- Massages can also be helpful.
- Rest well, get plenty of sleep.
- To avoid developing pressure sores, change your position at least every two hours.
- Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
- Stay hydrated, drink plenty of water.
Patients Concern
Disease/Condition Glossary
Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.
Arthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.
FAQs
TIZANIDINE+ACECLOFENAC contains Tizanidine and Aceclofenac. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac works by blocking the effect of prostaglandins, thereby reduces mild to moderate pain and inflammation.
TIZANIDINE+ACECLOFENAC is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.
Diarrhoea might be a side-effect of TIZANIDINE+ACECLOFENAC. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Dry mouth could be a side-effect of TIZANIDINE+ACECLOFENAC. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevents drying of the mouth.
Taking TIZANIDINE+ACECLOFENAC can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking TIZANIDINE+ACECLOFENAC if you have gastrointestinal bleeding or other bleeding problems like haemophilia before using TIZANIDINE+ACECLOFENAC.
