Tolperisone Hydrochloride+paracetamol
About Tolperisone Hydrochloride+paracetamol
Tolperisone Hydrochloride+paracetamol belongs to the class of medicine called 'muscle relaxant' in combination with a painkiller, used to treat muscle spasms. It improves the movement of muscles and provides relief from pain and discomfort caused by the muscle spasm. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.
Tolperisone Hydrochloride+paracetamol is a combination of two drugs: Tolperisone hydrochloride (muscle relaxant) and Paracetamol (pain killer). Tolperisone hydrochloride is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.
Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Tolperisone Hydrochloride+paracetamol include nausea, vomiting, dry mouth, dizziness, weakness, and sleepiness. These side effects are not familiar to everyone and vary individually.
Let your doctor know if you use any prescription and non-prescription medications before starting Tolperisone Hydrochloride+paracetamol. Inform your doctor if you have any liver, heart, or kidney diseases, myasthenia gravis (muscle weakness), and phenylketonuria (a genetic disorder that causes an amino acid build-up, phenylalanine) and alcohol dependency. Consult your doctor before taking Tolperisone Hydrochloride+paracetamol if you are pregnant or planning for pregnancy. Tolperisone Hydrochloride+paracetamol may cause dizziness, so drive only if you are alert and focused. Tolperisone Hydrochloride+paracetamol should not be given to children as safety has not been established. Avoid consuming alcohol and Tolperisone Hydrochloride+paracetamol as it could lead to increased dizziness and risk of liver damage.
Uses of Tolperisone Hydrochloride+paracetamol
Medicinal Benefits
Tolperisone Hydrochloride+paracetamol treats muscle spasms and consists of Tolperisone hydrochloride (muscle relaxant) and Paracetamol (pain killer). Tolperisone hydrochloride is a centrally acting muscle relaxant. It works on the spinal cord and brain to relieve contraction or muscle stiffness. It also increases the supply of blood to the muscles. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It inhibits cyclo-oxygenase (COX) enzymes that further prevent the formation of chemical messengers called 'prostaglandins' (PGs). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site.
Directions for Use
Storage
Side Effects of Tolperisone Hydrochloride+paracetamol
- Nausea
- Vomiting
- Dry mouth
- Dizziness
- Weakness
- Sleepiness
Drug Warnings
Inform your doctor if you have any liver, heart, or kidney diseases, myasthenia gravis (muscle weakness), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency before starting Tolperisone Hydrochloride+paracetamol. Consult your doctor before taking Tolperisone Hydrochloride+paracetamol if you are pregnant, planning for pregnancy, or breastfeeding. Tolperisone Hydrochloride+paracetamol may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Tolperisone Hydrochloride+paracetamol as it could lead to increased dizziness and risk of liver damage. Tolperisone Hydrochloride+paracetamol is not recommended in children as safety and efficacy is not established.
Drug Interactions
Drug-Drug Interaction: Tolperisone Hydrochloride+paracetamol may interact with anticoagulants (warfarin), drugs treating vomiting (metoclopramide, domperidone), cholesterol-lowering medications (cholestyramine) and anti-cancer medications (imatinib).
Drug-Food Interaction: Alcohol consumption may cause dizziness and increases the risk of liver damage.
Drug-Disease Interaction: Before using Tolperisone Hydrochloride+paracetamol, let your doctor know if you have any liver, heart or kidney diseases, myasthenia gravis (fatigue of muscles), phenylketonuria (a genetic disorder that causes a build-up of an amino acid, phenylalanine), and alcohol dependency.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid alcohol consumption while taking Tolperisone Hydrochloride+paracetamol. Alcohol intake, along with Tolperisone Hydrochloride+paracetamol, may cause increased dizziness and risk of liver damage.
Pregnancy
cautionTolperisone Hydrochloride+paracetamol should be used with caution during pregnancy. Please consult your doctor before taking Tolperisone Hydrochloride+paracetamol.
Breast Feeding
cautionTolperisone Hydrochloride+paracetamol should be used with caution during breastfeeding. Please consult your doctor before taking Tolperisone Hydrochloride+paracetamol.
Driving
cautionTolperisone Hydrochloride+paracetamol may make you feel dizzy. Do not drive or operate machinery if you experience dizziness.
Liver
cautionPlease consult your doctor since Tolperisone Hydrochloride+paracetamol should be used with caution in patients with liver impairment/liver disease.
Kidney
cautionPlease consult your doctor since Tolperisone Hydrochloride+paracetamol should be used with caution in patients with kidney impairment/kidney disease.
Children
unsafeTolperisone Hydrochloride+paracetamol is not recommended in children as safety and efficacy is not established.
Habit Forming
Diet & Lifestyle Advise
- Exercise regularly as it helps in muscle stretching and makes muscles less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
- Massages can also be helpful.
- Avoid freezing and hot temperatures.
- Avoid wearing tight-fitting clothes, instead, wear loose garments.
- Rest well and get plenty of sleep.
- To avoid developing pressure sores, change your position at least every two hours.
- Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.
- Stay hydrated, drink plenty of water.
Special Advise
- Let your doctor know that you are taking Tolperisone Hydrochloride+paracetamol if you are undergoing any medical tests.
- Tolperisone Hydrochloride+paracetamol may cause fluid retention (edema), hence it is advised to monitor blood pressure and cardiovascular status in patients with a heart failure history.
- Explain a detail history to the doctor as use of Tolperisone Hydrochloride+paracetamol is contraindicated in patients with myasthenia gravis.
Patients Concern
Disease/Condition Glossary
Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body.
Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or may feel tight or hard, like a knot.
FAQs
Tolperisone Hydrochloride+paracetamol is a combination of two drugs: Tolperisone hydrochloride and Paracetamol. Tolperisone hydrochloride works on the spinal cord and brain to relieve contraction or muscle stiffness. Paracetamol works by blocking the action of certain chemical messengers that cause pain.
Tolperisone Hydrochloride+paracetamol is usually used for a short period and can be discontinued if there is no pain. However, it should be continued if advised by the doctor.
Tolperisone Hydrochloride+paracetamol is to be carefully administered in patients with alcohol dependency, kidney or liver damage, myasthenia gravis (muscle weakness) and phenylketonuria (a genetic disorder that causes the build-up of an amino acid, phenylalanine). Please consult your doctor before starting Tolperisone Hydrochloride+paracetamol if you have a medical history.
Tolperisone Hydrochloride+paracetamol may cause stomach upset. Hence, you are recommended to take Tolperisone Hydrochloride+paracetamol with food to prevent stomach upset.
