Tranexamic Acid+mefenamic Acid
About
Tranexamic Acid+mefenamic Acid is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, Tranexamic Acid+mefenamic Acid is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, are characterized by cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.
Tranexamic Acid+mefenamic Acid is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.
You are advised to take Tranexamic Acid+mefenamic Acid for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Consult your doctor if you are pregnant or breastfeeding. Tranexamic Acid+mefenamic Acid may cause dizziness, so drive with caution. Tranexamic Acid+mefenamic Acid should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Tranexamic Acid+mefenamic Acid as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.
Uses of Tranexamic Acid+mefenamic Acid
Medicinal Benefits
Tranexamic Acid+mefenamic Acid is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. Tranexamic Acid+mefenamic Acid is used to treat abdominal pain, dysmenorrhea (period pain), and menorrhagia (heavy menstrual bleeding). Additionally, Tranexamic Acid+mefenamic Acid is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic agent that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Tranexamic Acid+mefenamic Acid helps treat heavy bleeding and pains/cramps during periods.
Directions for Use
Storage
Side Effects of Tranexamic Acid+mefenamic Acid
- Nausea
- Vomiting
- Diarrhoea
- Indigestion
- Heartburn
- Headache
- Musculoskeletal pain
- Stomach pain
In-Depth Precautions and Warning
Drug Warnings
Do not take Tranexamic Acid+mefenamic Acid if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Tranexamic Acid+mefenamic Acid may cause dizziness and drowsiness, so drive only if you are alert. Tranexamic Acid+mefenamic Acid should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Tranexamic Acid+mefenamic Acid as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with Tranexamic Acid+mefenamic Acid unless prescribed.
Drug Interactions
Drug-Drug Interactions: Tranexamic Acid+mefenamic Acid may interact with pain killers (ibuprofen, celecoxib), anti-depressant (duloxetine, fluoxetine, sertraline), fibrinolytic medicine, birth control pills, drugs that prevent bleeding (factor IX complex, anti-inhibitor coagulant concentrates), blood thinners (anticoagulants such as warfarin, heparin)
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: Inform your doctor if you have deep vein thrombosis, pulmonary embolism (blockage of blood vessels in the lungs), coagulopathy (formation of blood clots), epilepsy, peptic ulcers, asthma, glaucoma, gastrointestinal toxicity, high blood pressure, or heart problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Tranexamic Acid+mefenamic Acid as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.
Pregnancy
cautionPlease consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor before taking Tranexamic Acid+mefenamic Acid if you are breastfeeding, your doctor will decide if Tranexamic Acid+mefenamic Acid can be taken by breastfeeding mothers or not.
Driving
cautionTranexamic Acid+mefenamic Acid may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.
Liver
cautionDose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Kidney
cautionDose adjustment may be needed in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Children
unsafeTranexamic Acid+mefenamic Acid should not be given to children as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.
- Stay hydrated; drink plenty of water.
- Cut down on sugars, salts, spicy food, coffee, and alcohol.
- A heating pad can help ease the pain by placing it on the belly or lower back.
- Exercise can help ease the pain of menstrual cramps.
- Avoid stress by performing meditation or yoga.
- Massage your lower back or abdomen to relieve the pain.
- Take proper rest.
Patients Concern
Disease/Condition Glossary
Menorrhagia: Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods. The exact cause of menorrhagia is unknown, but it could be due to hormonal imbalance, dysfunction of the ovaries, uterine fibroids, polyps, inherited bleeding disorders, intrauterine devices, or medications. Symptoms include socking through one/more sanitary pads/tampons for every hour, needing to use double sanitary protection to control the flow, needing to wake up during the night to change the pad, bleeding for more than a week, passing blood clots, unable to do daily activities due to heavy flow, tiredness, and fatigue.
Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps, and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Symptoms of dysmenorrhea include intense throbbing pain in the lower abdomen, dull, continuous aches, pain in the lower back and thighs, nausea, headache, and dizziness. The pain usually starts 1-3 days prior to the period, peaks one day before the period starts, and subsides 2-3days after the onset of the period.
FAQs
Tranexamic Acid+mefenamic Acid contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.
Diarrhoea might be a side-effect of Tranexamic Acid+mefenamic Acid. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.
Tranexamic Acid+mefenamic Acid should not be taken for longer durations unless prescribed by the doctor. Tranexamic Acid+mefenamic Acid is usually prescribed for a few days at the time of heavy bleeding and cramps.
Tranexamic Acid+mefenamic Acid is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Tranexamic Acid+mefenamic Acid only as prescribed and do not overdose.
Consult your doctor before taking contraceptive pills along with Tranexamic Acid+mefenamic Acid. When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually legs).
Tranexamic Acid+mefenamic Acid contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Tranexamic Acid+mefenamic Acid if you have heart-related problems unless prescribed by the doctor.
