Nebivolol+hydrochlorothiazide
About
Nebivolol+hydrochlorothiazide belongs to the class of anti-hypertensives primarily taken to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. Nebivolol+hydrochlorothiazide is a combination medication generally used when a single medicine cannot control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.
Nebivolol+hydrochlorothiazide contains nebivolol and hydrochlorothiazide. Nebivolol is a beta blocker that works on the heart particularly to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time.
Nebivolol+hydrochlorothiazide should be taken as the doctor prescribes based on your medical condition. You may experience nausea, constipation, diarrhoea, fatigue, headache, dizziness, decreased potassium level in the blood, increased blood uric acid, altered blood lipid level, breathlessness, swelling of hands & feet, paresthesia (burning sensation of the skin), decreased magnesium level in the blood, increased calcium level in blood. Most of these side effects of Nebivolol+hydrochlorothiazide do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Before taking the Nebivolol+hydrochlorothiazide, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Before taking Nebivolol+hydrochlorothiazide, inform your doctor about your medical history and other medications you are currently taking to rule out any potential negative effects. It is recommended not to take Nebivolol+hydrochlorothiazide if you are pregnant or breastfeeding.
Uses of Nebivolol+hydrochlorothiazide
Medicinal Benefits
Nebivolol+hydrochlorothiazide is a combination of Nebivolol (beta-blockers/ blood pressure-lowering medicines) and Hydrochlorothiazide (thiazide diuretic or water pill). Nebivolol is a beta blocker that works on the heart specifically to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time. Thus Nebivolol+hydrochlorothiazide lowers blood pressure and prevents the risk of stroke, heart attack and oedema (fluid overload).
Directions for Use
Storage
Side Effects of Nebivolol+hydrochlorothiazide
- Nausea
- Constipation
- Diarrhoea
- Fatigue
- Headache
- Dizziness
- Decreased potassium level in the blood
- Increased blood uric acid
- Altered blood lipid level
- Breathlessness
- Swelling of hands & feet
- Paresthesia (burning sensation of the skin)
- Decreased magnesium level in the blood
- Increased calcium level in the blood
In-Depth Precautions and Warning
Drug Warnings
Before using Nebivolol+hydrochlorothiazide, inform your doctor if you have liver disease, kidney disease, eye problem (glaucoma), asthma, increased uric acid level (gout), diabetes, hyperlipidemia (increased level of lipid) or hyperthyroidism (increased level of thyroid). Nebivolol+hydrochlorothiazide should not be given to people allergic to Nebivolol+hydrochlorothiazide, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. It is contraindicated in low blood pressure (hypotension) and aortic stenosis (heart valve problem). Nebivolol+hydrochlorothiazide can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Nebivolol+hydrochlorothiazide and breastfeeding.
Drug Interactions
Drug-Drug Interactions: Nebivolol+hydrochlorothiazide may interact with other diuretics, blood pressure-lowering drugs (amiodarone, amlodipine, clonidine, digoxin, diltiazem, disopyramide), mental illness medications (amisulpiride, chlorpromazine, haloperidol), depression medications (amitriptyline, fluoxetine, paroxetine), antispasmodic medication (baclofen), anti-cancer medications (cyclophosphamide, fluorouracil, methotrexate), mood stabilizer (lithium), angina medication (bepridil), blood sugar-lowering medicines (insulin and oral antidiabetic drugs, metformin), medicines for gout (allopurinol, probenecid, sulfinpyrazone), drugs used to treat low blood pressure or slow heart rate (noradrenaline). If you are taking any of the above, speak with your doctor.
Drug-Food Interactions: You are recommended not to consume alcohol with a Nebivolol+hydrochlorothiazide to avoid unpleasant side effects.
Drug-Disease Interactions: Nebivolol+hydrochlorothiazide may interact with disease conditions, including liver function impairment, Anuria (severe renal insufficiency), cardiovascular diseases, Hypotension, bronchospasm (bronchial asthma), abnormal levels of potassium, calcium, sodium and symptomatic hyperuricemia (excess of uric acid in the blood).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol and Nebivolol+hydrochlorothiazide to avoid unpleasant side effects like drowsiness and dizziness.
Pregnancy
unsafeNebivolol+hydrochlorothiazide is not recommended during pregnancy. Nebivolol+hydrochlorothiazide contains hydrochlorothiazide that crosses the placenta. This may cause fetal damage and can affect the unborn baby (fetus).
Breast Feeding
unsafeTell your doctor if you are breast-feeding or about to start breast-feeding. Nebivolol+hydrochlorothiazide is not recommended for mothers who are breast-feeding.
Driving
cautionNebivolol+hydrochlorothiazide usually causes drowsiness and dizziness, affecting your ability to drive or operate machinery.
Liver
cautionNebivolol+hydrochlorothiazide to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your current liver conditions.
Kidney
cautionNebivolol+hydrochlorothiazide to be taken with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust your dose depending on your current kidney conditions.
Children
cautionLimited information is available regarding the usage of Nebivolol+hydrochlorothiazide in children, so please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
- Keep your weight under control with a BMI of 19.5-24.9.
- Avoid chronic stress, as it can raise your blood pressure.
- Spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Be mindful of salt; consume no more than 2,300 mg each day.
- Limit or avoid alcohol consumption.
- Quitting smoking is the best strategy to lower the risk of heart disease.
Special Advise
- Your doctor may advice regular blood sugar monitoring as Nebivolol+hydrochlorothiazide may cause changes in your blood sugar levels.
Patients Concern
Disease/Condition Glossary
Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.
FAQs
Nebivolol+hydrochlorothiazide contains nebivolol and hydrochlorothiazide. Nebivolol is a beta blocker that works on the heart to lower heart rate and make the heart more efficient at pumping blood throughout the body. The diuretic hydrochlorothiazide lowers blood pressure by removing excess water and electrolytes from the body. It also relaxes blood vessels and improves blood flow over time.
Nebivolol+hydrochlorothiazide can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
In case you have missed a dose of Nebivolol+hydrochlorothiazide, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both the doses together. Take only one dose, taking a double dose of Nebivolol+hydrochlorothiazide will lead to low blood pressure.
Yes, Nebivolol+hydrochlorothiazide can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Nebivolol+hydrochlorothiazide. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
