Lamivudine+tenofovir Disoproxil Fumarate
About
Lamivudine+tenofovir Disoproxil Fumarate belongs to a class of drugs called antiretrovirals used to treat HIV infection. Lamivudine+tenofovir Disoproxil Fumarate helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.
Lamivudine+tenofovir Disoproxil Fumarate is a combination of two drugs, namely: Lamivudine and Tenofovir disoproxil fumarate. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Lamivudine+tenofovir Disoproxil Fumarate works by interfering with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Lamivudine+tenofovir Disoproxil Fumarate helps in treating HIV infection.
Take Lamivudine+tenofovir Disoproxil Fumarate as prescribed by your doctor. You are advised to take Lamivudine+tenofovir Disoproxil Fumarate for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, nausea, vomiting, diarrhea, weakness, or rash. Most of these side effects of Lamivudine+tenofovir Disoproxil Fumarate do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Lamivudine+tenofovir Disoproxil Fumarate or any other medicines, soya or peanut, please tell your doctor. If you are pregnant or planning for pregnancy, please consult a doctor before taking Lamivudine+tenofovir Disoproxil Fumarate. Avoid breastfeeding while taking Lamivudine+tenofovir Disoproxil Fumarate as it may pass into breast milk. Lamivudine+tenofovir Disoproxil Fumarate is not recommended for children below 18 years of age. You are recommended to avoid the consumption of alcohol with Lamivudine+tenofovir Disoproxil Fumarate as it may increase the risk of liver damage. Drive only if you are alert as Lamivudine+tenofovir Disoproxil Fumarate may cause dizziness.
Uses of Lamivudine+tenofovir Disoproxil Fumarate
Medicinal Benefits
Lamivudine+tenofovir Disoproxil Fumarate is a combination of two drugs, namely: Lamivudine and Tenofovir disoproxil fumarate used to treat HIV infection. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil fumarate is a nucleotide reverse transcriptase inhibitor. Lamivudine+tenofovir Disoproxil Fumarate interferes with the working of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, Lamivudine+tenofovir Disoproxil Fumarate helps in treating HIV infection. Taking Lamivudine+tenofovir Disoproxil Fumarate along with practicing safe sex and lifestyle changes may reduce the risk of getting or transmitting HIV to others.
Directions for Use
Storage
Side Effects of Lamivudine+tenofovir Disoproxil Fumarate
- Dizziness
- Nausea
- Vomiting
- Diarrhoea
- Weakness
- Rash
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to Lamivudine+tenofovir Disoproxil Fumarate or any other medicines, soya or peanut, please tell your doctor. If you are pregnant or planning for pregnancy, please consult a doctor before taking Lamivudine+tenofovir Disoproxil Fumarate. Avoid breastfeeding while taking Lamivudine+tenofovir Disoproxil Fumarate as it may pass into breast milk. Lamivudine+tenofovir Disoproxil Fumarate is not recommended for children below 18 years of age. You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. If you experience stomach pain, vomiting or nausea while taking Lamivudine+tenofovir Disoproxil Fumarate, please consult a doctor immediately as these might be symptoms of a rare but severe side effect known as lactic acidosis (excess of lactic acid in the blood). You are recommended to avoid consumption of alcohol with Lamivudine+tenofovir Disoproxil Fumarate as it may increase the risk of liver damage. Drive only if you are alert as Lamivudine+tenofovir Disoproxil Fumarate may cause dizziness.
Drug Interactions
Drug-Drug Interaction: Lamivudine+tenofovir Disoproxil Fumarate may have interaction with the antifungal drug (amphotericin B), antiviral (foscarnet, ganciclovir, cidofovir), medicines used to treat chronic hepatitis B infection (adefovir dipivoxil), immunosuppressant (tacrolimus), antibiotics (pentamidine, vancomycin), anti-cancer (interleukin-2).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have any infection, kidney or liver problems, inform your doctor before taking Lamivudine+tenofovir Disoproxil Fumarate.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption with Lamivudine+tenofovir Disoproxil Fumarate as it may increase the risk of liver damage.
Pregnancy
cautionLamivudine+tenofovir Disoproxil Fumarate is given to pregnant women if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.
Breast Feeding
unsafeAvoid breastfeeding while taking Lamivudine+tenofovir Disoproxil Fumarate as it may pass into breast milk. Therefore, please consult a doctor if you are breastfeeding.
Driving
cautionLamivudine+tenofovir Disoproxil Fumarate may cause dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel dizzy after taking Lamivudine+tenofovir Disoproxil Fumarate.
Liver
cautionTake Lamivudine+tenofovir Disoproxil Fumarate with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake Lamivudine+tenofovir Disoproxil Fumarate with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafeLamivudine+tenofovir Disoproxil Fumarate is not recommended for children below 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
- Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
- Avoid sharing used needles, other injections, or drug equipment.
- Get tested for other sexually transmitted infections such as gonorrhea or syphilis as they can make you prone to HIV infection.
- Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
- Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
- Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
- Try to reduce emotional and physical stress by spending time with family or doing whatever makes you happy.
Special Advise
Regular kidney and liver function tests, bone mineral density tests are recommended while taking Lamivudine+tenofovir Disoproxil Fumarate.
Patients Concern
Disease/Condition Glossary
HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.
FAQs
Lamivudine+tenofovir Disoproxil Fumarate contains Lamivudine and Tenofovir disoproxil fumarate. Lamivudine+tenofovir Disoproxil Fumarate works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes which are necessary for the reproduction of the virus. Together, Lamivudine+tenofovir Disoproxil Fumarate helps in treating HIV infection.
Lamivudine+tenofovir Disoproxil Fumarate may cause bone problems such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. However, if you experience joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.
HIV infection may still be transmitted to other persons while using Lamivudine+tenofovir Disoproxil Fumarate. Lamivudine+tenofovir Disoproxil Fumarate reduces the risk of transmission, but still, HIV infection is contagious. Therefore, discuss with a doctor regarding precautions to be taken to avoid transmission of HIV while taking Lamivudine+tenofovir Disoproxil Fumarate.
Lamivudine+tenofovir Disoproxil Fumarate does not cure HIV infection. Lamivudine+tenofovir Disoproxil Fumarate reduces the amount of HIV virus in the body and improves the functioning of the immune system.
Lamivudine+tenofovir Disoproxil Fumarate should be used with caution in patients with existing infections as it may worsen the infection. However, please consult a doctor if you notice any signs of infection or inflammation.
Lamivudine+tenofovir Disoproxil Fumarate may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver disease. However, if you experience stomach pain, vomiting or nausea while taking Lamivudine+tenofovir Disoproxil Fumarate, please consult a doctor immediately.
